| Source | |
| 1970 Census | 109,512 |
| 1980 Census | 122,453 |
| 1990 Census | 130,964 |
| 1998 Census | 133,618 |
| 2000 Census projection | 138,004 |
| 2015 Census projection | 145,831 |
| Tri-state area labor force: | 168,000 |
| Total population of counties within 50 miles of Dothan |
| 515,000 |
| Total population of counties within 500 miles of Dothan |
| 51,300,000 |
Source: Dothan Area Chamber of Commerce